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dextran sulfate sodium dss induced colitis acute colitis  (Valiant Co Ltd)

 
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    Valiant Co Ltd dextran sulfate sodium dss induced colitis acute colitis
    Dextran Sulfate Sodium Dss Induced Colitis Acute Colitis, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 98/100, based on 2087 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dextran+sulfate+sodium+dss+induced+colitis/Dextran/pm41927825-55-0-17
    Average 98 stars, based on 2087 article reviews
    dextran sulfate sodium dss induced colitis acute colitis - by Bioz Stars, 2026-09
    98/100 stars

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    Mouse Assay:

    Article Title: IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling
    Article Snippet: .. Dextran sulfate sodium (DSS)-induced colitis in mice was modeled by the administration of 1.5% or 2% (w/v) DSS (colitis grade, 36-50kDa, MP Biomedicals) in the drinking water for 7 days followed by normal water w/o DSS. (12-13) Oxazolone colitis was induced by intrarectal administration of 0.5% oxazolone (Sigma-Aldrich) in 50% ethanol via a 3.5 F catheter. (12 and 14) Mice were closely evaluated for survival, general condition, body weight, stool consistency and rectal bleeding, and disesase activity was scored based on previously described criteria. (12-13) The scoring of inflammation on endoscopy recordings was assessed by two investigators in a blinded manner. ..

    Activity Assay:

    Article Title: IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling
    Article Snippet: .. Dextran sulfate sodium (DSS)-induced colitis in mice was modeled by the administration of 1.5% or 2% (w/v) DSS (colitis grade, 36-50kDa, MP Biomedicals) in the drinking water for 7 days followed by normal water w/o DSS. (12-13) Oxazolone colitis was induced by intrarectal administration of 0.5% oxazolone (Sigma-Aldrich) in 50% ethanol via a 3.5 F catheter. (12 and 14) Mice were closely evaluated for survival, general condition, body weight, stool consistency and rectal bleeding, and disesase activity was scored based on previously described criteria. (12-13) The scoring of inflammation on endoscopy recordings was assessed by two investigators in a blinded manner. ..

    Sterility:

    Article Title: Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair.
    Article Snippet: Macrophages are crucial for the maintenance of intestinal homeostasis, are considered key proinflammatory effector cells during intestinal inflammation and are implicated in tissue repair following injury or inflammation.. Whether these roles are attributed to distinct subsets of macrophages or if macrophages retain a degree of plasticity in the intestine remains poorly understood.. Here, through a combination of single cell RNA sequencing, lineage-tracing and immunofluorescence imaging, we define three major subpopulations of murine, colonic macrophages on the basis of CD11c and CD163 expression.



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    Silencing CBX4 alleviates <t>DSS-Induced</t> UC in Mice. ( A ) Western blot analyses showing CBX4 expression in the colons of mice following knockdown. ( B ) Body weight change in different groups. ( C ) The Disease Activity Index (DAI) in different groups. ( D , E ) Statistical analysis of colon length. ( F ) H&E staining. Scale bar = 100 μm. Data were presented as mean ± SD, n = 6. *** p < 0.001. ### p < 0.001 vs. EV-DSS group.
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    Silencing CBX4 alleviates <t>DSS-Induced</t> UC in Mice. ( A ) Western blot analyses showing CBX4 expression in the colons of mice following knockdown. ( B ) Body weight change in different groups. ( C ) The Disease Activity Index (DAI) in different groups. ( D , E ) Statistical analysis of colon length. ( F ) H&E staining. Scale bar = 100 μm. Data were presented as mean ± SD, n = 6. *** p < 0.001. ### p < 0.001 vs. EV-DSS group.
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    Image Search Results


    Silencing CBX4 alleviates DSS-Induced UC in Mice. ( A ) Western blot analyses showing CBX4 expression in the colons of mice following knockdown. ( B ) Body weight change in different groups. ( C ) The Disease Activity Index (DAI) in different groups. ( D , E ) Statistical analysis of colon length. ( F ) H&E staining. Scale bar = 100 μm. Data were presented as mean ± SD, n = 6. *** p < 0.001. ### p < 0.001 vs. EV-DSS group.

    Journal: Biomedicines

    Article Title: Integrative Transcriptomics and Machine Learning Reveal the Association of CBX4 with Inflammation in Ulcerative Colitis as a Potential Epigenetic Regulator

    doi: 10.3390/biomedicines14030687

    Figure Lengend Snippet: Silencing CBX4 alleviates DSS-Induced UC in Mice. ( A ) Western blot analyses showing CBX4 expression in the colons of mice following knockdown. ( B ) Body weight change in different groups. ( C ) The Disease Activity Index (DAI) in different groups. ( D , E ) Statistical analysis of colon length. ( F ) H&E staining. Scale bar = 100 μm. Data were presented as mean ± SD, n = 6. *** p < 0.001. ### p < 0.001 vs. EV-DSS group.

    Article Snippet: A dextran sulfate sodium (DSS)-induced colitis model was generated with 2.5% DSS (MP Biomedicals, molecular weight 35,000–50,000 Da).

    Techniques: Western Blot, Expressing, Knockdown, Activity Assay, Staining